Right now there is a very popular style for cartoonish emotes in twitch. I made a LORA sampling 100+ emotes from many channels.
This LORA is a little hard to tame, but it works fine even mixed with other LORAs.
Best results are achieved by geting a base image for many emotes and just inpaint the face with many different keywords, then clean in an image editing software like photopea.

For best results appart than using the main trigger word "twitch emote" also use "white background, sticker"

I will add some examples of key prompts that you can use for similar results. (This emotes have been manually worked on for consistency and generated using inpainting and ControlNet along with the Lora)

disgusted, angry

laughing, eyes closed

sleeping, eyes closed (The Z were added manually)

crying, mouth open

moaning, panting, sweating, closed eyes, blush

holding text sign, hands up

holding a gun

Holding a red heart balloon